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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Gendered violence and women’s citizenship in Africa
2014-05-23

 
Prof Takyiwaa Manuh

Prof Takyiwaa Manuh celebrated both Africa Day and her birthday with the UFS on 22 May 2014.

Being the guest speaker at the Africa Day Memorial Lecture, Prof Manuh discussed how gendered violence and the lack of women’s true citizenship in Africa still hinder the Pan-African ideal. She asked the question: if African issues get less worldwide attention, how much less attention do African women get?

“Africa Day offers us an opportunity to revisit the Pan-African ideal and aspiration for total national liberation, equality and self-worth,” Prof Manuh said.

“This ideal has envisaged full citizenship with the enjoyment of rights and resources for the people of Africa to live a dignified and fulfilling life. Yet, the conceptions of citizenship that have emerged in several African countries do not fully incorporate women and girls.”

The lecture explored the policing of women’s bodies and sexualities and how their enjoyment of rights is undermined – often under the pretext of culture. Often families, communities, states, religious bodies and culture work collaboratively to mold African women into the patriarchal image of disciplined and virtuous. The epidemic of violence against females negates their fundamental human rights and their claim to full citizenship and protection within their states.

The lecture also reviewed recent efforts including law reform, legislation and actions by activists. “The African Union and the UN need to confront these violations and suggest a robust agenda for more effective exercise of women’s citizenship rights and convergence towards the Pan-African ideal.”

Prof Manuh is currently Director: Social Development Policy Division of the United Nations Economic Commission for Africa in Addis Ababa, Ethiopia.

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