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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Make the right choices and you will succeed, Prof Jansen advises learners
2014-05-30

“You can make a choice today that will end up with you being pregnant, having babies, being unemployed, sitting at home like some of our brothers and sisters, uncles and aunts. Or you can make a different decision – and that decision is about you working so hard that you earn entry into the University of the Free State, get your degree and become great, not only in South Africa, but in the world.”

This was the message from the UFS’s Vice-Chancellor and Rector, Prof Jonathan Jansen, who addressed prospective Kovsies during our Open Day on the Qwaqwa Campus on Saturday 24 May 2014. Prof Jansen advised all learners to always make the right decisions.

“The first right decision is to pass well. You must go for 60%, 70% and 80% passes. Set yourself a target and do not just strive to pass, but to pass well,” Prof Jansen told a packed Rolihlahla Mandela Multi-purpose Hall, with learners coming from as far as Ficksburg, Lindley and Koppies.

“The second thing that you need to do, is to believe in yourself. Do not believe people who tell you what you can or cannot do. Believe in what you can do,” said Prof Jansen.

“Thirdly, you have to get up and do things for yourself. You have to work hard, sleep less and study hard. Don't accept excuses. If you can do these three things, then the best place to study is the University of the Free State. Believe that the sky is the limit.”

“We learned a very valuable lesson here today,” said Tumelo Mofokeng from Nkarabeng Secondary School in Kestell.

The fun-filled programme included performances and messages of encouragement from current students who have been part of the unique Leadership for Change Programme. This programme equips first-year students with skills to reflect, dialogue and engage on issues of diversity and leadership.

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