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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Transforming lives through reading
2014-08-11

 
The UFS Library and Information Services visited Lekhulong Senior Secondary School as one of their community development projects commemorating Mandela Day on 25 June 2014. Situated in the Bloemfontein township of Rocklands, the school’s library was depleted of books and in need of a total revamp. The group of change agents under the guidance and leadership of Marcus Maphile, Assistant Director: Information Services, consisted of seventeen library staff members, library ambassadors and volunteers from Student Life and Leadership.

A total of 450 books were donated to the school. The range of books was made up of mainly dictionaries and encyclopaedias. Fifty of these copies were acquired through the ‘Buy or Donate a Book’ campaign run by the library earlier this year.

In thanking the UFS library, the school’s principal, Mash Mawasha said reading has always been a challenge for his learners and that he is confident that this will be a major turning point for them.

The Director of Library Services, Betsy Eister, expressed the UFS library’s commitment to this project. She pledged regular visits to the school to ensure that Lekhulong library staff are trained on how to run the library and that teachers include library books in their teaching.

“We try to ensure that by the time learners arrive at universities,” Maphile said, “they have exposure to libraries, that they acquire a love for reading books and most importantly have confidence not only to express themselves but to use the library system efficiently.”

The book donation programme has been running successfully for two years and apart from revitalising school libraries in disadvantaged communities, the UFS library staff provides training and support to teacher librarians. Next year, the team plans to extend their project to another community in Bloemfontein – that of Headstart High School.


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