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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Internet Broadcast Project wins at International Enterprise Video Awards
2014-08-11

Video: Internet Broadcast Project

In April this year, the ICTISE (ICT Innovation in School Education) division won the first place at the Enterprise Video Awards held in Madison, Wisconsin, USA. Their Internet Broadcast Project (IBP) was the overall winner in the Innovation category – competing against universities and other training institutions from across the world.

The IBP is a collaborative project between the ICTISE and the Free State Department of Education (FSDoE). Broadcasting from the South Campus studio in Bloemfontein, teachers use specialised web-casting technology to present lessons that reach 68 education centres. Lessons cover a range of subjects and broadcast in real time to teachers and learners from Grades 8 to 12, covering 40 Free State towns, including the most rural areas.

Head of the ICTISE Project, Sarietjie Musgrave said, “Each participating school is equipped with 24/7 uncapped internet access, an all-in-one computer (computer, data projector and sound system), a document camera and a printer – the same equipment used in the studio by the expert teachers.

“The technology provided allows learners to communicate with the expert teacher in the studio during a broadcast to the school or learner at no cost. Lessons can be downloaded on to various devices and re-used during teaching time, shared with neighbouring schools, or taken home by learners to help with homework or for revision.

“To date, the IBP catalogue contains over 2 000 video lessons and during 2013 alone, the 68 schools accessed and used these videos 69 305 times. The project has the potential to reach more than 40 000 learners and 1 765 teachers every week.”

Innovation and sustainability form the backbone of this project. Support is provided to teachers and learners in Mathematics, Maths Literacy, Physical Science, Life Science, Geography, English, Accounting, Economics and Business Studies.


The ICTISE has a dedicated technical team to support schools. During broadcasts there is a dedicated helpline and on-site technical support, even in the remotest areas.

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