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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsies deliver eight Brightest Young Minds
2014-08-15


Front, from the left: Michael van Niekerk, Thabiso Letselebe and William Clayton; Back, from the left: Gopolang Kgaile, Thokozane Mahlanga and Mpho Sefo; Lisa Coetzee and Lehlohonolo Mofokeng were not present during the taking of the photograph.

Eight Kovsies have been selected as part of 100 delegates for the 2014 Brightest Young Minds (BYM) summit.

Thabiso Letselebe (Chief Delegate of the UFS BYM), Michael van Niekerk, William Clayton, Gopolang Kgaile, Thokozane Mahlanga, Mpho Sefo, Lisa Coetzee and Lehlohonolo Mofokeng will attend the BYM summit from 29 August to 2 September 2014 in Johannesburg.
BYM is a youth-driven non-profit organisation that identifies South Africa’s most passionate young people. The organisation equips these young leaders with the skills and networks needed to create positive change.

Each year, 100 participants are invited to a five-day summit, based on criteria of innovation, leadership, civic responsibility and academic accomplishment. Delegates discuss challenges facing the nation with respected leaders and then design start-up like solutions to these challenges.

Post-summit alumni have access to resources for success and BYM continues to encourage social entrepreneurship. BYM has demonstrated success in mobilising young people for nearly fifteen years.

BYM has been the launch pad for several successful business and social endeavours. Some of the ideas developed by BYM alumni include the AIDS Industry Management Standard, Taxi Smart Card System, MiniSass Water Monitoring System, Investec Young Women in Finance conference, Tertiary School in Business Administration, Twenty30 and Women in Engineering.

BYM attracts a diverse group of participants in terms of academic, racial, geographic and socio-economic backgrounds. In a society marred by divides, BYM is proving the power of diversity. The organisation’s participants would not be as successful in moving the nation forward if it were not for the diversity of their experience.

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