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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Six of our students on their way to Stanford Sophomore College
2014-08-21


Back, from the left are: Philip Kitsopoulos (BCom Law), Ulrich Kristen (Medicine)
and Stephan Erasmus (Medicine).

The university hosted a send-off function for our students who are about to attend a three-week seminar at Stanford Sophomore College (SoCo).

Six Kovsie students were selected to attend the seminar at the Stanford SoCo in September 2014. This programme is an immersive learning experience where participants attend class meetings during the morning. Their afternoons include class activities, explorations of Stanford, field trips as well as organised events.

UFS students were invited to apply for one of six SoCo courses in February 2014. After months of apprehension, the successful Kovsie applicants were announced in May this year.

These outstanding Kovsie students and the courses they will attend are:

  • Sebabatso Makafane, Vuyisile Kubeka and Philip Kitsopoulos – New Millennium Mix: Crossings of Race and Culture;
  • Ulrich Kristen – Resistance Writings in Nazi Germany;
  • Kaylene Pillay – Ghost Stories: Why the Dead Return and What They Want From Us; and
  • Stephan Erasmus – Responses to the AIDS Epidemic.

During the farewell function, Rudi Buys: Dean of Student Affairs, handed the students their flight tickets and visas. This was followed by messages of support from Dr Lis Lange, Directorate for Institutional Research and Academic Planning, and Prof Neil Roos from the Centre for Africa Studies.

Prof Roos concluded the evening’s programme with some advice for these students. “Don’t go there and come back to copy the students and personalities you meet there. Go there and show your own characteristics to them.”

The six Kovsies will depart on 29 August and return home on 19 September 2014.

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