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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Young Communication student publishes second book
2014-09-03

Most people get to 90 and never publish a book. Some people at 19 have not even read a book.
But 19-year-old BA Communication student at Kovsies, Grace Nthebe, has already published two books, only in this year...

Grace writes poetry and her first book is called Reflections by Grace.

“It is a personal book and it was only by the grace of God that I could do this reflection,” says Grace.

“Reflections take a look at four aspects of myself:

- Me as a beginner in my life;
- Being a believer of love;
- Looking at critical conditions in life;
- And then finally, taking a look at myself as an African woman.”

Grace became fascinated with poetry in Grade 10. She developed as a poet more and more when she was in Grade 11 and started relying on her writing as a means to express the unexpressed.

“A friend of mine took a look at my writing and asked why I don’t have it published?”

“That was not easy, but I covered everything smoothly and took my time with it.”

More recently, Grace’s second book called Tribute to Love was also published.

“This is more of a motivational book,” she says.

“Young women often have to pretend to be ‘okay’ when going through tough times like a break-up. In Tribute to Love I go through ten basic steps to recover fully after a break-up.”

“A lot of times recovery starts with forgiveness and if you have social support, it eventually ends with learning to let go and being willing to love again. Relationships and break-ups are often phases every person goes through, but it is important to go through it in the right way…”

Grace’s books are self published by Quick Fox and available online at amazon.com

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