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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Business breakfast nurtures key partnerships
2014-09-05

 

Dr Reuel Khoza

In growing and nurturing key projects and initiatives, the university hosted more than fifty partners and alumni at a business breakfast in Sandton, Johannesburg on 27 August 2014. The occasion was conceived by Institutional Advancement in collaboration with the Office of the Vice-Chancellor and Rector.

Discussions focused on the central role which institutional partnerships play in growing the university’s capacity to extend its reach in supporting schools and growing technologically-based educational tools for disadvantaged communities around the Free State and the country at large.

In his remarks, Prof Jansen thanked partners for their continued support and for joining hands with the university in supporting key projects and initiatives that have improved the level of education in the Free State, provided skills development and nurtured young leaders.

The guest of honour Dr Reuel Khoza, non-Executive Chairman of Nedbank and co-host Dr Marcus Ingram, Director of Institutional Advancement, discussed the role of meaningful leadership in the African context and social and political structures that are instrumental in developing future leaders. As stated simply but powerfully by Dr Khoza, “If not us, then who?”

In attendance were heads of corporations, key role players in partner organisations and NGOs, alumni and Corporate Social Investment specialists from leading financial institutions. 
 

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