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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

New SANRAL Chair in Science, Mathematics and Technology Education
2014-09-19

 

MEC: Butana Khomphela
Photo: Jerry Mokoroane

The University of the Free State (UFS) in partnership with the South African National Roads Agency launched the SANRAL Chair in Science, Mathematics and Technology Education on the Bloemfontein Campus on 11 September 2014. Prof Loyiso Jita has been appointed as the first SANRAL Chair. He is a professor in the School of Mathematics, Natural Sciences and Technology at the UFS, where he shares his expertise in science teaching, which has been influenced by his broad and deep intellectual and experiential engagements both internationally and domestically.

Speaking at the event were Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS; Dr Choice Makhetha, Vice-Rector: External Relations; Prof Jita, the inaugural SANRAL Chair; the Free State MEC for Police, Roads and Transport, Mr Butana Komphela and Mr Nazir Alli, CEO of SANRAL.

At the event, Prof Jansen celebrated that “SANRAL has rewarded the faith in our children to do well in science and mathematics with this Chair.”

This SANRAL Chair in Science, Mathematics and Technology Education will help to improve the quality of teaching in these vital subjects at schools in the province. It complements the university’s School Partnership Project (SPP) – a flagship initiative launched by Prof Jansen.

The SANRAL endowment will enable the university to hone in on the ‘gateway subjects’ of mathematics and natural science. At school level, it will help to train teachers, support student-teacher interns, and incentivise education results so that participating schools become centres of excellence. At an academic level, the SANRAL Chair will supervise a cohort of doctoral and masters students, while also guiding research and publications in mathematics, science and technology education.

Through the endowment, SANRAL will assist the UFS in producing education leaders who can turn around maths and science education in disadvantaged schools throughout Southern Africa.

For the full text, read: New SANRAL Chair in Science, Mathematics and Technology Education

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