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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Active citizenship key to building healthier communities
2014-09-22

Photo: Mamosa Makaya

The Office of Community Engagement in collaboration with Bloem Shelter, hosted a three-day Indaba on active citizenship. The focus of the event was to engage local government leaders, NGOs and social services groups on creating a society that is healthier, safer and more informed.

The over-arching theme of the Indaba centred on the strengthening of family structures, social and health service delivery, spiritual healing and counselling. Amongst the various speakers was Rev Jennifer Samdaan, Minister in the Methodist Church and community activist. During her presentation, ‘Youth, Women and Children at Risk in South Africa', she highlighted the challenges that women and youth in townships and rural areas deal with in their daily lives. One example is physical and sexual violence while commuting to school and work. Rev Samdaan’s organisation has been instrumental in engaging municipal authorities in the region of Kokstad to provide security and lighting on roads where women are most vulnerable to violent attacks as they commute from work.

Community workers discussed their contributions in the fields of marital and family counselling and mental health support services. They discussed the benefits of their collaboration with local judicial bodies and other community leaders to render services to victims of domestic violence.

Rev Billyboy Ramahlele, Director in the Office of Community Engagement, emphasised the role of leadership and the responsibility of political leaders and citizens alike to ensure accountability in the quest to build a healthier society.

Vanessa Booysen, a neonatal consultant for Newborn Care in South Africa, demonstrated the importance of bonding between mothers and their babies. She called attention to the negative effects on the development of babies when separated from their mothers and the future challenges this causes. Modern medicine also leads to fewer women giving birth naturally. Booysen stressed that "it matters how we are born". She encouraged health practitioners to go back to basics in maternal care to lessen the negative effects that pass onto children into adulthood.

The workshop concluded with an exhibition by various groups that showcased the information resources and services offered to communities in the Free State.

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