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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Student performers dazzle at Kovsie Extravaganza
2014-10-01

The Kovsie Extravaganza is an annual highlight on our university’s Arts and Culture calendar. The event offers outstanding Kovsie artists the opportunity to showcase their talent in music, dance and poetry – to name but a few – live on stage. The Sand d u Plessis theatre in Bloemfontein was packed to capacity for this highly-anticipated performance on 27 September 2014.

With the multi-award winning a cappella trio, The Soil, and Kovsie Idol Delia Moumakwe included in the line-up, tickets were already sold out nine hours before the show.

But the Kovsie acts by no means paled in comparison to these stars. In addition, the Free State Youth Orchestra – which includes some of the most talented students at our Odeion School of Music – provided an inspired performance.

This full production had the crowd dancing, cheering and clapping throughout the ecvent. The size and reaction of the audience was firm proof of the Kovsie Extravaganza’s growing popularity.

Speaking to Ntsika Ngxanga, a member of The Soil, he said that they were truly blessed to have made it this far in the music industry. Growing up in Soweto in difficult circumstances, the trio is now performing on stages across the globe. “We thank the UFS for their support towards the extravaganza. We definitely wish the student community all the best with their studies. Education is important,” Ngxanga said.

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