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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Mosa Leteane introduces new era in student leadership
2014-10-02

The month of August belonged to South African women – in more ways than one. Not only did we celebrate Women’s Month, but our Student Representative Council (SRC) gained a female leader.

On 4 September 2014 Mosa Leteane became the first female SRC president at the UFS Bloemfontein Campus under the revised SRC constitution of 2011. Although her journey has been a hard and difficult one, it rewarded her with great insightful and invaluable experience.

Being elected to this seat is a milestone for female leadership as a whole at Kovsies. Having been the Prime of House NJ van der Merwe Residence, Marketing Officer of the premier Golden Key Society, Executive Committee member for the 2013/2014 SRC Legal and Constitutional Affairs – and being a legal student herself – Leteane brings a lot of experience to student governance.

Accountability is one of her core values– and that is exactly what she envisions to bring to the newly-elected SRC. Leteane also believes that having a moral sense is essential to the functioning of her SRC. Being a political science or legal student does not automatically imply high morals, Leteane adds. Rather, principles are fostered by the contribution that you want to make.

Something she is proud to have inherited from the previous SRC is the establishment of a blueprint for student governance and understanding team dynamics. These things define the success of any SRC.

With the amount of work lying ahead, Leteane says, she will draw strength from family and friends – and listen to some music.

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