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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Waldo Staude shares his vision
2014-10-13



Waldo Staude has recently been announced as our new Vice-President of the Student Representative Council (SRC) on the Bloemfontein Campus. And one thing that becomes clear as soon as you meet him, is his passion for leadership.

As a first-year, Staude was a resident in JBM Hertzog. This experience – living on campus together with his fellow students – gave him great insight into the dynamic of human relationships.

By joining the SRC and becoming the Vice-President, Staude believes that he will bring about positive change. "We all tend to complain that 'ja, the SRC doesn't do their job,'” Staude says. But it’s an entirely different reality, he explains, when you are actually in the situation yourself and trying to make a difference.

Through voting, he continues, students not only have an opportunity to raise their concerns, but they exercise their power to become pro-active on campus. "You can take a step and guide this university where it needs to go," he says.

Staude – currently studying BSc Agric – has great faith in South Africa. His dream and vision is to ultimately uplift as many of our country's people as he possibly can.


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