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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Leadership for Change celebrates graduation ceremony
2014-10-15

The Leadership for Change Programme hosted its third annual graduation ceremony on 9 October 2014 at the Centenary Complex on the Bloemfontein Campus.

The event consisted of two segments. The first was aimed at the group who has travelled abroad during the past year. They were presented with special certificates acknowledging the work they have done during their participation in the programme.

The second element of the evening was to wish the 2014/2015 group all of the best for their upcoming travels. This group will be travelling abroad during next year. Of the 250 applicants, the top 32 students were chosen to be part of the Leadership for Change Programme.

Prof Jonathan Jansen, Vice-Chancellor and Rector, said, “I hope you came back with the capacity to distinguish right from wrong – not only through law, but morally as a leader.”

Waldo Staude, Vice-president of the Student Representative Council (SRC), acted as Chair to the evening’s proceedings. He is also an alumnus of this programme.

“This programme has made its mark as we observe the number of leadership positions our students from the programme hold on this campus,” Staude said. “We have eight Leadership for Change students in the SRC for the 2014/15 term.”

The Leadership for Change Programme each year gives first-year students exposure to top universities throughout the world. Its focus is to establish a new campus culture of student relations across boundaries.

Six cohort groups – of between five to six students each – will visit universities on three different continents in January 2015. Each group will be accompanied by a UFS staff member serving the role of mentor.

The universities they will be visiting (according to continent), are:

 USA
Cleveland State University
University of Minnesota
University of Vermont 

Europe
The Netherlands: Vrije University in Amsterdam
Belgium: University of Antwerp and Ghent University 
 
Asia
Japan: International Christian University

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