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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

New SRC Sport talks about campus pride
2014-10-21

Media Studies and Journalism student, Dominique de Gouveia, can attest to the fact that you need to take all the small steps before you make the giant leap.

As Residence Committee member for Sport since her first year, Dominique found the transition to the Student Representative Council (SRC) merely a case of now putting on the striped blazer. Having worked closely with Lourika Hugo, previous SRC Sport, there was not really much that she had to take grasp of.

“Our varsity has almost the same sport fixtures every year, so once you understand it, it should not be that difficult to follow through,” says Dominique confidently.

“You need to set goals in order to achieve them. I quickly realised that this is what I want to do. Sport is very big on our campus among the students and in my term I want other channels to realise the importance of sport.”

“The motto of previous SRC Sport, Tshepo Moli, was ‘transformation in sport’, which can indeed make a social impact on our varsity.”

“Through sport, our varsity can take pride in showing diversity.”

The variety of sports Dominique enjoys playing and watching, shows just how much she really loves what she is doing.

“My favourite sports have to be soccer and squash. But after watching the Varsity Netball this season, it made me wish that I had learnt how to play netball as far back as high school.”

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