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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Samuel Masingi dreams of a shared vision
2014-10-31

Newly-appointed Student Representative Counsel (SRC) member, Samuel Masingi, holds high aspirations for his 2014/2015 term. He has been elected to the portfolio of Ex officio: Student Media Council. Masingi aims to bring the media and students closer together.

“If the media platforms are solid,” Masingi says, “then everything else will just fall into place, causing a snowball effect. I think this is very critical, because even if you do great things, there is no point if no one knows about it.”

A believer in an open door policy, Masingi encourages students to visit him to share their ideas and opinions.

Masingi credits ambition and hard work for his achievements and the success in his academic career. He believes that confidence and willpower can convert ambition into accomplishment – transforming dreams into reality. Studying for his honours in Sport Sciences, Masingi believes in stepping up to the task at hand and making an impact. Be an agent of change in order to see the difference you desire.

Having formerly served on the Tswelopele Residence Committee for Sport, Masingi is not new to the media scene. He previously gained experience as the Sports Editor of the IRAWA Post. He currently contributes to various publications which include Student Leverage – an online magazine – and News24 Voices. This makes him highly -suitable to head the student media portfolio.

When asked about his hopes for the 2014/2015 Student Representative Council he replied, “A shared vision.”

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