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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Three Kovsies receive prestigious Mandela Rhodes scholarship for 2015
2014-11-10

From the left: Lehlohonolo Mofokeng, Tumelo Morobane and Zola Valashiya
Photo: Stefan Lotter

 

The UFS continues to produce leaders and is proud to have three Mandela Rhodes scholars next year.

Lehlohonolo Mofokeng, Zola Valashiya and Tumelo Morobane all received this prestigious scholarship for 2015.

A Mandela Rhodes Scholarship provides full funding for a maximum of two years of postgraduate study. The award is open to all African citizens under the age of 30 years and recipients must study towards an honours or master’s degree at a recognised South African institution. Although there is no maximum number of awards, the scholarships are highly competitive, with fewer than 30 scholarships being awarded each year since its inception in 2005. The scholarships cover tuition, accommodation, meals, book allowance, general allowance, and travel expenses. Recipients of the Mandela Rhodes Scholarship are students with outstanding academic achievements, who also possess leadership ability, entrepreneurial skills, and a commitment to reconciliation. In addition to receiving funding for their studies, scholars also do a leadership development programme while in residence. The award is named after Nelson Mandela and Cecil Rhodes and is administered by the Mandela Rhodes Foundation, which is a partnership between the Nelson Mandela and the Rhodes Trusts.

Lehlohonolo has just finished his BEd Hons in Philosophy and Policy of Education at the UFS. He hopes to enroll for a master’s degree in Education Policy, Planning and Management at the University of Witwatersrand with his Mandela Rhodes Scholarship.

Zola is originally from Johannesburg and is completing his LLB degree at the UFS this year. He is planning to stay at the UFS in 2015 to do his LLM in Constitutional Law or International Human Rights Law.

Tumelo has a BSc Honours in Actuarial Science and will use this scholarship next year to study towards her master’s degree at the UFS.

“I chose to stay at the UFS because I am doing a great master's project with Munich Re through the UFS,” says Tumelo. 

“Furthermore, the CEO of the Mandela Foundation, Mr Sello Hatang, asked me to work with the foundation on a few projects that mostly focus on keeping the girl child in school across Africa, as well as helping with providing training and workshops on entrepreneurship to young people.

“So, I am looking forward to a very busy year ahead of me, which will be filled with so much learning, growth and making a difference,” Tumelo says.

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