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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Department of Architecture recognises excellence
2014-11-20

 

From the left are: Gary Westwood, Marius du Plessis and Henry Pretorius
Photo: Ifa Tshishonge
Front page design by Marius du Plessis

Marius du Plessis received the first prize in the Regional Corobrik Student of the Year Award for his design of a National Geothermal Research and Educational Centre in Johannesburg. The award ceremony was hosted by the Department of Architecture at the University of the Free State.

Anja Lareman was awarded the second prize for her Psychiatric Unit for the Deaf in Worcester and Mariska Peel received third prize for her design of a laboratory for the after oil epoch in Durban.

The Corobrik award for Best use of clay masonry brickwork was awarded to Valentino Moutzouris for his design of a Performing Arts Centre in Wynberg, Cape Town.

The event was well attended by architecture students who hoped to take home an award. Projects exhibited, received distinctions in one or all of the three main components, including design, the architectural theoretical treatise and building sciences.

“This is the greatest award that one could win in the Free State. It came with so much blood, sweat and tears, as I had to live, eat and work day and night at the same place in order to finish the project,” said Marius, master’s student in Architecture. He said that he hopes the project can be developed and implemented in mine shafts to solve the energy crisis in South Africa.

Henry Pretorius, Academic Departmental Head of Architecture, said: “It is vital for architecture to have a public interface. This event is to showcase the work of students and to make sure that it is accessible to the public. It encourages students to understand the value of their own work and its cognisance to society.”

Gary Westwood, Sales Manager of Corobrik Free State, Northern Cape and Lesotho region, said: “So far it has been an incredible journey. This annual event of 24 years is our way of giving back to the community who supports and sustains our business. It is wonderful to see how the architecture industry has adapted to a more sustainable way of design, by being part of the green movement.”

Marius will compete with other Corobrik winners from various universities on national level in April 2015.

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