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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsies among top SADC debaters
2014-11-26

From the left are: Matlhodi Leteane and Lehakoe Masedi.

The UFS Debate Society is definitely not all talk and no action. They ranked 10th at the Southern African Development Community (SADC) Debate Open held in Gaborone, Botswana, from 14 – 16 November 2014.

Kovsie students Lehakoe Masedi (second-year BCom Law) and Matlhodi Leteane (first-year LLB Law) teamed up to represent our university at the prestigious SADC event hosted by the University of Botswana Speaking Union. Eight Southern African countries were represented as well as six universities from South Africa.

“Attending a tournament focused on the debating of regional issues and solutions was a great reward and we wish to take part in more of these tournaments in future,” says Lehakoe.

Out of a pool of 40 of the best individual speakers in Southern Africa, Lehakoe and Matlhodi were jointly awarded 18th place.

“Debate continues to help the growth of the student community and the attendance of such debate tournaments lends a lot of help to the internal growth of not only our partnership but our debate society as a whole,” says Lehakoe. “We take great pride in our performance, especially as first-year *British Parliamentary speakers. We wish to improve and grow as we progress further in our debate careers.”

*British Parliametary speaking is the style of debating used by university institutions.

 

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