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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Odeion String Quartet receives international acclaim
2014-12-22

 

The Odeion String Quartet (OSQ) is a flagship of the UFS and symbolises the university’s commitment to the arts. Most recently, the OSQ walked away with the award for Best Classical Music Performance at the 2014 Kanna ceremony.

It was established in 1991 as a permanent full-time resident string quartet –   at present the only resident string quartet at a South African university – and functions as an independent academic department at the UFS.

The members of the quartet are Samson Diamond (leader and first violin), Sharon de Kock (violin), Jeanne-Louise Moolman (viola) and Anmari van der Westhuizen (cello). They have an extensive national and international background and are highly regarded in music circles as soloists and chamber musicians. The members of the quartet play an important strategic role in the development of symphony orchestra music and in classical music training in the Free State. They are exemplary teachers and attract students from all over the country. The Junior Odeion String Quartet and Odeion Sinfonia provide a unique chamber music training experience to selected students.

They regularly perform to critical acclaim in all the major music centres in South Africa, as well as in SADC countries such as Zimbabwe and Zambia. During 2013 they performed at concerts in Belgium, Germany and Switzerland, where they received standing ovations and very positive reviews.

The quartet is also set on giving back to musical communities around the country, with workshops offering guidance on playing techniques and life-skills that are essential for young people who intend to pursue a career in the music sector.

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