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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Three of UFS Unit for Language Management to international congress
2006-06-12

Three members of the University of the Free State's (UFS) Unit for Language Management (ULM), namely Prof Theo du Plessis (Director of the ULM), Prof Johan Lubbe (Research Associate of the ULM) and Dr Elbie Truter (Research Associate of the ULM), will be attending the Tenth International Congress of the International Academy of Linguistic Law at the University of Galway, Ireland, from 14-17 June 2006. 

This year, the theme of the congress will be “Language Law and Language Rights: The Challenges of Enactment and Implementation”.  More than 100 persons will deliver papers at this congress, which enjoys prominent status world-wide.  The UFS colleagues are all members of the International Academy of Linguistic Law, and will deliver papers offering perspectives on language regulation within the South African context. 

Other South Africans who will also be participating, and with whom the ULM has close professional relationships, are Dr Karel Prinsloo (editor of the well-known journal 50 Plus) and Mr Edward Sambo of the Pan South African Language Board (Pansalb).  The ULM’s participation in the congress is the result of a long-term research project, namely, the South African Language Rights Monitor, which was launched three years ago in partnership with Pansalb, and which is also financed by that organisation.


Prof Theo du Plessis
(Director of the UFS Unit for Language Management)

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