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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

National Astronomy Symposium at Boyden
2006-08-29

The Astronomical Society of Southern Africa (ASSA) will hold its 7th National Symposium at the Boyden Observatory, Bloemfontein from 28 - 30 September 2006.

The event is being organised by the Bloemfontein branch of ASSA in association with Boyden Observatory, which is linked to the Department of Physics at the University of the Free State (UFS).

Registration is open to the public. The symposium affords interested persons the rare opportunity to get behind the scenes of Southern African astronomy and to attend presentations by speakers such as Prof. Phil Charles (SAAO),  Dr. Adrian Tiplady (SKA/KAT),  Dr. Patrick Seitzer (University of Michigan, USA), Prof. David Block (WITS) and Tim Cooper (ASSA).

60-inch UFS Boyden reflector telescope. Photo: Hannes Calitz

An exciting program awaits participants. Various demonstrations and presentations relating to some of the latest developments in amateur astronomy will be presented.

The Symposium will include an "astronomy presentation workshop" where a national astronomy presentation competition will be launched.

A special tour of the facilities at the Boyden Observatory will take place on Thursday evening, 28 September, and participants can see astrophysical research in action when they are shown one of the three large operational optical telescopes in Africa.

Join professional and amateur astronomers from all over the country on Friday evening, 29 September, for a memorable dinner to commemorate the 10th anniversary of the Friends of Boyden, to be held at Kopano Nokeng Lodge.

Bloemfonteiners are especially encouraged to make use of this unique opportunity.

 For more information and a registration form visit:

Web: www.assabfn.co.za/symposium2006


 

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