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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Bloemfontein Campus hosts annual HELTASA conference
2014-12-09

 

From the left are: Prof Francois Strydom, Director: Academic - Centre for Teaching and Learning, UFS; Dr Lis Lange, Vice-Rector: Academic, UFS; and Prof George Kuh, Adjunct Research Professor of Education Policy at the University of Illinois.

This year, the privilege to host the annual Higher Education Learning and Teaching Association of Southern Africa (HELTASA) conference was afforded to our university. The event took place on the Bloemfontein Campus from 18 – 21 November 2014, attracting keynote speakers and members from across the world.

HELTASA is a professional association mainly for educators and significant role players in higher education institutions. With its inception in the early 2000s, it has grown to become the premier organisation for teaching and learning in Southern Africa, Dr Amanda Hlengwa, President of HELTASA, pointed out.

A central concern of this body is issues around success within the tertiary sector. The theme of this year, ‘Accessing success: using evidence for change’ served to focus members’ attention on what works and what does not work – as derived from researched evidence.

In a message from Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), he stressed that the task as university teachers “is not simply cognitive gains that ensure graduation success but also intellectual gains that ensure success in life during and after university studies.”

The conference was led by internationally-acclaimed keynote speakers, namely Prof George Kuh, Prof William Grabe and Prof Fredricka Stoller, as well as our own A1 NRF-rated Prof Malanie Walker.

Prof Kuh is Adjunct Research Professor of Education Policy at the University of Illinois and Chancellor’s Professor of Higher Education Emeritus at Indiana University. In his keynote address, Prof Kuh offered valuable lessons from the field to promote student success.

Profs Grabe and Stoller collectively presented the second keynote address that explored how to set up students for success through strategic-reader training. Prof Grabe is Regents’ Professor of Applied Linguistics and Vice President for Research at Northern Arizona University. Prof Stoller is a Professor of English at Northern Arizona University, where she teaches in the MA-TESL and PhD in Applied Linguistics programmes.

Prof Walker is a Senior Research Professor at the UFS Centre for Research on Higher Education and Development (CRHED). She is also currently Director of Research Training and a senior researcher in the EU-funded Marie Curie EDUWEL project. In her keynote address, Prof Walker looked at well-being and agency in higher education.

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