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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Chancellor’s Medal awarded to Tokkie Pretorius for outstanding service to the community
2014-12-12

Tokkie (JL) Pretorius – a qualified attorney who obtained his BProc, LLB and LLM at the University of the Free State (UFS) – was the recipient of the prestigious Chancellor’s Medal on 11 December 2014 during our Summer Graduation Ceremony. This latest honour builds on a path of achievements, being a previous recipient of both a Dean’s Medal as well as the Juta Prize for the best law student at the UFS.

The Chancellor’s Medal is awarded to an individual for outstanding service or achievement at local, national or international level, or for service to the community or the UFS. The academic component of a candidate’s contribution or achievement may be taken into account, but will not be decisive.

Pretorius was General Manager: Legal Services at the Free State Development Corporation (FDC) from 1996 – 2009 and Company Secretary from 2004 – 2009. Since 2009, he has been the CEO of the Anglo-Boer Museum in Bloemfontein.

“It is a great honour for me to receive the Chancellor’s Medal,” said Pretorius – who was nominated for the Bloemfonteiner of the Year competition in 2011.

“The medal is awarded to me at a very relevant time for the museum as well. The museum is at a time where nation-building, diversity and transformation are priority. Therefore, the Chancellor’s Medal award is an indication of the close co-operation between the museum and the UFS, both of whom are focused on the promotion of nation building, diversity and transformation,” Pretorius said.

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