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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof Helene Strauss delves into the emotion and politics of contemporary South African protest cultures
2014-12-22

Prof Helene Strauss from the University of the Free State’s (UFS) Department of English currently researches the relationship between emotion and politics in contemporary South African public and protest cultures.

The research foregrounds the complex set of concerns opened up by a study of intimacy, read as not simply a sign for emotional and sexual closeness, but more broadly as a complexly mediated site from which to observe the embodied, affective coordinates of various forms of control and contestation. Through the analysis of a range of cultural texts that, for instance, recompose moments of spectacular social upheaval through the lenses of everyday, embodied experience, this research considers what aesthetic responsibility might mean in both post-transitional South Africa and elsewhere.

One aspect of this research charts a gradual shift in South Africa from what is frequently referred to as the ‘liberation euphoria’ of the mid- to late 1990s – and the optimistic fantasies of a future South Africa that characterised dominant public discourse in the period immediately following the political transition – toward an emotional culture in which expressions of anger, disillusionment and disappointment seem to have become relatively widespread.

Prof Strauss asks, for instance, how these public feelings have been managed in the aftermath of events such as the Marikana massacre, and suggests that the affective and temporal dimensions of current attempts at containing perceived threats to financial and political stability on the part of South Africa’s business and political elite are key to understanding increasingly violent and repressive securitisation strategies.

Earlier this year, Prof Strauss presented papers on aspects of this research at two international conferences: (i) the Association for Cultural Studies conference in Tampere, Finland, where she was invited to be part of a ‘Spotlight Panel’ on the topic of African Cultural Studies, (ii) and at a conference at McMaster University in Hamilton, Canada, which she helped to co-organise.

An article based on some of this work has been published in the journal Safundi.

For more of Prof Strauss’s research published in journals, follow the links below:
http://www.tandfonline.com/toc/rsaf20/current#.VAf88_mSxqU
http://www.tandfonline.com/toc/riij20/15/1#.VAf80vmSxqU
http://www.palgrave-journals.com/sub/journal/v4/n2/index.html

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