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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

When entrepreneurship meets industrial innovation
2014-12-13

Johan Eksteen (Photo: Supplied)

Internationally acclaimed Argicon Pelleting is a worldwide supplier of pelleting machinery and equipment as well as agri-processing factories. The company was established in 1993 by André and Johan Eksteen, UFS 2004 MBA graduate. After taking over sole ownership, the company grew from a one-man business to an internationally respected specialist in the design and manufacturing of pelleting solutions for the agricultural industry.

A common practice in industrial procedures, pelleting involves processing material into small dry pellets. This is used globally by manufacturers of animal feed or recycling facilities that specialise in processing materials for reuse. This process, however, can only be successfully accomplished with specialised equipment, namely a pelletizer. With fifteen years’ experience in agriculture, and international exposure in countries such as Uganda, Australia, Singapore and New Caledonia, this was not a tall order for Johan.

Agricon focuses on consistently developing innovative ways to add value to its offering. The business has successfully installed pelleting equipment for a range of products, including tobacco dust, rooibos tea, human sludge waste, organic fertilizers and vermi-compost. In addition to the manufacturing of machines and equipment, the company also provides training and on-site installation for clients, as well as support following a sale or the provision of spare parts. The company also provides advice on new product developments and business opportunities for clients within the sector.

Apart from doubling its sales between 2013 and 2014, the company gained great recognition within the industry. Johan was awarded the University of the Free State Business School’s Entrepreneur award in 2013 and he is the first-prize winner of the ILO Free State EnterPRIZE Job Creation Challenge for 2014. He is currently one of 15 finalists countrywide in the Entrepreneur of the Year competition sponsored by Business Partners and Sanlam. Johan is the mentor and stand-in manager for Almenta, a skills development company (winner of the ILO Best Social Entrepreneur for Skills Development award) and Equus Groom School (winner of the ILO Social Entrepreneur in Youth Development award).

Johan was also announced as the winner of the SA entrepreneur of the year for small businesses.

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