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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof Magda Fourie is visiting the University of Oxford
2004-08-30

 

Prof Magda Fourie, Vice-Rector: Academic Planning at the University of the Free State (UFS), is currently visiting the University of Oxford in the United Kingdom where she is doing research at the Institute for the Advancement of University Learning.

 

The primary role of the Institute is giving effect to the Teaching and Learning Strategy of Oxford University by supporting the quest for excellence in learning, teaching and research at the university. Prof Fourie will pay particular attention to research that the Institute has done on creating an optimal learning environment for students, with the purpose of enhancing the learning environment of students at the UFS.

Prof Fourie was awarded a University of Oxford Fellowship by the Association of Commonwealth Universities to spend two months at Oxford University for professional development purposes.

She will also visit the Oxford University Department for Continuing Education, the Office for Distance and Online Learning and the Planning and Resource Division.

Prof Fourie’s visit abroad will be concluded with a visit to Dundee in Scotland, where she will attend a conference for vice-chancellors and deputy vice-chancellors on managing change in higher education. She will return to South Africa by the middle of next month.

 

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