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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS council awards honorary doctorates
2007-03-22

The Council of the University of the Free State (UFS) has decided to confer honorary doctorates on architect Prof. Barend Johannes Britz and author Mr Khotso Pieter David Maphalla.

Prof. Bannie Britz is being honoured for his contribution to architecture and Mr Maphalla for his contribution to the development of the Sesotho language and culture.
Prof. Britz worked as an architectural assistant abroad as well as in South Africa between 1961 and 1964, before establishing his own practice in 1968. He obtained a master’s degree in Urban Design in 1991 and was awarded the Prize of the City of Johannesburg for the best urban design dissertation.

He was appointed as Professor and Head of the Department of Architecture at the UFS in 1992. Prof. Britz is a member of several professional associations and has received 17 merit awards as well as a gold medal of excellence from the Institute of SA Architects.

Mr Maphalla is a prolific Sesotho author and has contributed significantly to the development of the Sesotho language and culture through his poetry, novels, dramas and short stories.

Most of his books have been prescribed for secondary schools throughout the country. His collected works are still used as reference works for literary studies by African Languages Departments at most South African universities.

Mr Maphalla played a significant role in the establishment of the South African National Sesotho Authors’ Association and has been the recipient of numerous awards for his sterling work. These include the M-net Book Prize in 1996 and a Lifetime Achiever Award in 2005 from the National Department of Arts and Culture, the first and only Sesotho author to have received this award thus far.

Media release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@mail.ufs.ac.za
19 March 2007
 

 
Prof. Bannie Britz

 
Mr. Khotso Pieter David Maphalla

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