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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Soetdoring/Kagiso pair-up wins 2015 Stagedoor
2015-03-03

With a new format and residences mixing it up, the 2015 Stagedoor proved to be a success yet again, leaving Soetdoring and Kagiso with the spoils of victory.

Stagedoor (the annual first-year residence stage and serenade competition) saw a change of format this year where residences were combined to perform in a few number of outdoor venues for rotations.

Prior to this, Residence CoRC Cultures expressed much concern regarding the co-operation that might (or might not) be achieved with working with other residences. These were all early stage fears. However, as their preparations progressed there seemed to be a glint of light at the end of many groups’ tunnels.

Seven diverse and combined groups made it through to final, namely;

• Vishuis and Tswelopele,
• Karee and Armentum,
• Sonnedou and NJ van der Merwe,
• Soetdoring and Kagiso,
• Roosmaryn and Vergeert-My-Nie,
• Villa Bravado and Madelief, and
• and Veritas and Marjolein.

The finals proved that the efforts and sleepless nights of RC Cultures, first-years, composers, and other behind-the-scenes contributors can really make any situation work.

As always, the crowd was blown away by the musical and vocal talent of first-years, as some compositions gave the audience goose bumps, leaving them asking for more. All in all, the evening created a frenzy, causing residences to interact whereas they would have never done so before.

According to the Student Affairs’ Arts and Culture office, the aim behind the new format was to break the barriers between residences. Arts and Culture were also pleased as to with how the RCs worked around accommodating their partners and ensuring maximum co-operation, despite some challenges.

As the night neared its closeclosing, residences were chanting their names and showing their pride in their first years’ performances.

2015 Stagedoor final results:

1. Soetdoring and Kagiso
2. Roosmaryn and Vergeet-My-Nie
3. Vishuis and Tswelopele

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