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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

SRC Arts and Culture speaks up
2015-03-17

"Stagedoor was an absolute success," says fourth-year medical student, Stefan van der Westhuizen and SRC member for arts and culture.  

 

"I've always been a diverse person and exposed myself to many things."

 

Raised in Vanderbijlpark near Johannesburg, Stefan has always had a passion for arts and culture.

 

"It's a platform where students express so much. Stagedoor is where you can see students express their commentary on what is happening on campus and feel like it’s almost a safe zone."

 

Stefan’s year on the SRC brought about a new format to rotations. Residences paired with each other, while the new 'outdoor' interactions made it possible for residence and off-campus students to interact with rotations.

 

"I was most proud of the rotations that took place even at the Agricultural Building. There was some great interaction," he said.

 

Stefan said the idea was to fix things.

 

“Not much had changed with Stagedoor when I got into office, even ticket sales were decreasing. I wanted to get students amped about it again."

 

A different element of Stagedoor 'outdoor' was to try to get spontaneity, and to try to get away from residences doing the same plays, but get them out of their comfort spot.

 

“When we heard the results, we lit up with excitement because we didn't have the usual winners,” Stefan said.

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