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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Knowledge sharing key to community building
2015-03-19

From the left: Prof Mabel Erasmus (UFS Service Learning) and Dr Ruth Albertyn (Stellenbosch University).
Photo: Mamosa Makaya

The Office of Community Engagement facilitated a workshop and book launch attended by NPO partners, PhD students, and university staff from various departments, on 11 and 12 March 2015 on the Bloemfontein Campus.  The book entitled Knowledge as Enablement between higher education and the third sector, written by Prof Mabel Erasmus from the Service Learning office and Dr Ruth Albertyn from Stellenbosch University, was the centre of discussion, during which the authors opened the floor to the audience to do a chapter-by-chapter analysis and discussion session.

The book makes a significant contribution to research concerning third-sector organisations, and highlights the value which they bring into engagement work.  Dr Choice Makhetha, Vice Rector: External Relations, officiated at the book launch. She applauded the valuable research and hard work that had gone into the project. Some of the workshop topics include ethics and knowledge sharing, technology and communication, social entrepreneurship and the challenges of shared value systems faced by NPOs.

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