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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Juan Odendaal on his way to World Champs
2015-03-23

Juan Odendaal
Photo: BOOGS Photography, Andrew McFadden

UFS’s athletes with disabilities are currently excelling in cycling and athletics.

The UFS Para-cyclist, Juan Odendaal, will soon make his debut for South Africa at the 2015 Union Cyclist International (UCI) Para-cycling Track World Championships in Apeldoorn, The Netherlands, from 26-29 March 2015.

The Championship event will provide an excellent foundation for re-building the international competitiveness of South Africa’s Para-cycling track team in the build-up to Rio 2016. In a situation where the UCI has hosted relatively few international track competitions over the past three years, the 2015 World Championships will serve as a stepping-stone to the 2016 grand season, when it is expected that the country’s top riders will reach their peak competitive condition.

As the youngest member of the South African team, Odendaal will use the opportunity of competing in the individual time trial and team sprint events to build a platform for an international career will certainly span many years to come.

Another UFS student, Musa Simelane, are excelling and was chosen for the SA Wheelchair Rugby tean, known as the "Wheelboks". They will compete in the 2015 World Wheelchair Rugby Challenge in London in October and after that head to Japan to compete in the 2015 Asia Oceania Championships.

On a local level, earlier in March this year, other UFS athletes with disabilities also performed well on the athletics track.

Blind athlete and member of the Bloemfontein Campus Student Representative Council (SRC), Louzanne Coetzee, also had a good 1500m race in the beginning of March when she qualified easily for the World Championships, which will take place in Toronto, Canada, later this year. Coetzee and her guide, Rouxné Jacobs, set up a time of 5:45.86, which is well under the required standard of 6 minutes.

The other blind UFS athlete, Danie Breitenbach, alongside his guide Marius Wessels, broke his own national record for the 800m again on Friday 6 March 2015. In November 2014, Breitenbach’s record stood at 2:15.17. This record now stands at 2:13.57. Chances now are that Breitenbach will reach his goal of running the 800m under 2:10 at the Nedbank National Championship for the Physically Disabled at the end of March 2015.

The other Kovsie stars who will be participating at the Nedbank National Championship for the Physically Disabled are as follows:

Athletes:
• Dineo Mokhosoa
• Louzanne Coetzee
• Danie Breitenbach
• Juanré Jenkinson
• Diederich Kleynhans
• Jacques de Bruyn

Swimmer:
• Johann van Heerden

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