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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

"Participation without insight leads to pronouncements without prospects"
2004-08-30

Taking the poor off the streets and encouraging their participation in the planning process is not always empowering them but it might be robbing them of their power, said Prof Das Steyn, of the Department of Urban and Regional Planning at the University of the Free State (UFS).

Speaking on public participation in the planning process during his inaugural lecture, Prof Steyn said this meant that people in the streets sometimes have more power than people in the system.

“Public participation is an overgeneralization that is often defined as providing citizens with opportunities to take part in governmental decisions and planning processes. But there must be a balance between power and responsibility,” he said.

According to Prof. Steyn, public participation in town planning plays a vital role and can be both deliberation and participation.

After 1994 there was a widespread insistence on democracy, and legislation passed since then was based on the belief that the community must be involved in the planning process.

He said the experience of the Department of Urban and Regional Planning at the UFS was that in some cases people showed lack of interest in public participation.

He believed that the aim of public participation is to improve the effectiveness of planning and that public participation democratises project planning.

“Public participation can help us know how the public feels about certain issues. It has the potential of resolving a conflict, but this is not guaranteed,” Prof Steyn said.

 

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