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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

“We have to be ashamed as South Africans in these xenophobic attacks” – Dr Khotso Mokhele
2015-04-17

In a show of solidarity, the staff, students, and graduates at the University of the Free State hosted various events to remember those victims of recent Xenophobia attacks in the country.

During the Autumn Graduation this week on the Bloemfontein Campus, a moment of silence was observed at the different ceremonies.

At the ceremonies, UFS Chancellor, Dr Khotso Mokhele, said these graduations are not only about the graduates’ success but also about keeping in mind those who are being killed in our own country because their countries could not uphold them.

“All of us as South Africans should show a displeasure at the xenophobic attacks that have taken place in the country. These acts are inhumane, and we have to be ashamed as South Africans.”

South Africa has been rocked these recent weeks by various flares of attacks on foreign nationals living in South Africa. Five people or more have died in these attacks.

The Institute for Reconciliation and Social Justice at the UFS also started hosting conversations to create awareness and understanding among the Kovsie community about xenophobia and the subsequent hate crimes.

In spite of diverging opinions, different approaches, and the complexities at the heart of the issue, everyone at these discussions agreed that xenophobia needs to be addressed urgently, not only by government, but also by every South African citizen.

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