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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

One from UFS elected as Vice-President of ASAQS
2015-04-20

Stephen Ramabodu and Dr Marléne Campbell, Stephen’s promotor during his studies.
Photo: Leonie Bolleurs

The university is very proud of the election of Dr Stephan Ramabodu, from the Department of Quantity Surveying and Construction Management, as Vice-President and the chairman of the fees committee of the Association of South African Quantity Surveyors (ASAQS).

ASAQS aims to advance and promote the science and practice of quantity surveying, uphold the dignity of the quantity surveying profession, and promote the high standards of professional competence and integrity, among other things. Members of the ASAQS receive guidance and resources to succeed in quantity surveying, and to stay abreast of developments in the built environment today and in the future.

The ASAQS also provides an environment in which professionals may learn, grow, and work together to advance the techniques and science of quantity surveying. The ASAQS include quantity surveying professionals from every area of the construction industry, from private practice, government and quasi-government organisations to construction companies.

Stephan completed his quantity surveying (QS) degree as well as a master’s degree in Land and Property Management at the University of the Free State. In 2014, he completed his PhD, making him the first black South African PhD holder in the Department and one of the few QS PhD holders nationwide. 

In 2002, Stephen was appointed as a lecturer in the Department of Quantity Surveying and Construction Management under a programme called Grow Your Own Timber. He went to gain some commercial experience in Cape Town, where he worked for Davis Langdon. In 2008, he came back to the Free State, where he established Ramabodu & Associates Later that year, he returned to the university as a lecturer to complete all the remaining milestones of the Grow Your Own Timber programme.

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