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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS to host second Global Leadership Summit
2015-07-02

 

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The Global Leadership Summit (GLS) will be held at the University of the Free State’s (UFS) Bloemfontein and Qwaqwa Campuses between 5 July and 17 July 2015.

More than 103 international delegates from various universities in Asia, the United States, and Europe, as well as 40 student delegates from the University of the Free State, are expected to attend.

Keynote speakers will include local and international academics, thought leaders, and local celebrities, such as Prof Pumla Gobodo-Madikizela, Zelda le Grange and Donna Walker-Kuhne.  This is the second time that the UFS hosts the GLS. The first time was in July 2012, when it was a great success and was attended by about 160 international and local delegates. 

This year, panel discussions and workshops will focus on gender issues, citizenship and leadership, race relations and interfaith leadership. The summit will strengthen formal and informal international academic partnerships, sharing the emerging UFS international network with its partner organisations, while expanding opportunities for new cooperative initiatives, and enhancing international exposure of UFS staff and students by creating opportunities for vibrant intercultural interaction and exchange on campus. 

New possibilities for participation in international research partnerships in diverse research areas will be explored, as well as issues relating to diversity and transformation and the exchange of ideas and international experiences that contribute to the rethinking of curricula and educational approaches in Higher Education.

As part of the programme, delegates will visit the Qwaqwa Campus on 10 July 2015, where they will interact with the leadership of the campus, its staff and students and enjoy the arts and cultural experience of the Eastern Free State.  The summit will end with a visit to various sites in Bloemfontein, where delegates will engage in community-based outreach activities in disadvantaged communities around the city.

More about the Global Leadership Summit

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