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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Researcher in Plant Breeding one of nine women on the African continent to receive acknowledgement for work in food security
2015-08-04

 
 Prof Maryke Labuschagne

Prof Maryke Labuschagne, Plant Breeding researcher in the Department of Plant Sciences at the University of the Free State (UFS), is one of only nine women on the African continent to receive the prestigious ‘Country Lifetime Achiever Award’ from Africa’s Most Influential Women in Business and Government Programme (MIW) this year.

During a breakfast event, CEO Communications recognised the Most Influential Women in SADC South who are Building Nations. The event took place at the Vodacom Dome in Midrand on 28 July 2015.

She received the award for her commitment and continuous contributions to food security. “I am concerned about this. We need to develop people who can go into Africa to work together for food security on the continent,” says Prof Labuschagne.

Prof Labuschagne
and her students’ research focuses on the genetic improvement of food security crops in Africa, including such staples as maize and cassava. “These crops are genetically improved for yield, drought tolerance, disease, and insect resistance, as well nutritional value.”

“Food security is one of the key factors for stability and prosperity on the continent,” she says.

Apart from the fact that her research is helping to provide food for thousands of people on the continent, she is also an NRF-rated researcher, and author or co-author of over 160 articles in accredited journals.

This is not the firstaward that Prof Labuschagne has received for her work. In 2008, she was chosen as the National Agriculturalist of the Year by the Agricultural Writers Association of South Africa. In 2012, she received the Researcher of the Year award from Grain South Africa, as well as the African Union’s Kwame Nkrumah Science Award for Life Sciences on the continent. 

The Country Lifetime Achiever Award is a prestigious award that recognises and honours the lifelong efforts, achievements, and contributions by individuals in their local communities. This recognition covers all sectors and countries, to create a platform where the work and involvement of extraordinary people can be displayed and noted.

About the award, Prof Labuschagne says: “It is always great to be recognised for your work.”

Elana Meyer (athlete) and Thuli Madonsela (Public Protector and advocate) have also received awards from the programme this year.

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