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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Team UFS flexes its debating muscles
2015-08-07


Photo: Nkahiseng Ralepeli debates his way to the finals of the English as a First Language category at the UCT Open.

Team UFS flexes its debating muscles

Friday 24 July 2015 marks the day when the University of the Free State Debating Society (UFDS) outperformed the University of Cape Town (UCT) at the UCT 150th anniversary celebration of its debating union.

Representing Kovsies were Zola Valashiya, Ntsapi ‘Neko, Nkahiseng Ralepeli, Lehakoe Masedi, and Thabang Thembani, who fought bravely for a spot in the finals.

Masedi and Ralepeli broke into the semifinals after seven preliminary rounds, eventually winning the competition. The two students were up against three UCT teams, comprising the current National Champions and Pan African finalists.

This follows the debaters’ outstanding performance at the 2015 South African National University Debating Championship (SANUDC), hosted by the University of Venda. The UFDS commemorated a decade in existence by participating in its 10th national tournament.

After nine preliminary rounds, two teams broke into the grand finals of the two categories: English as a second language (ESL) and English as a first language (EFL). Devon Watson and Nkahiseng Ralepeli were the EFL team who fought their way through to the finals, beating UCT and the University of Botswana.

The inaugural Wits Women’s Debate Open (2014) title holders, Lerato Leteane and Lehakoe Masedi, represented Kovsies as the ESL finalists against the University of Nambia. The ladies rose to the occasion, but eventually emerged just one point short of the Namibian team’s four-point win.

Nonetheless, they were satisfied with their competitive skills, utilising the platform to address the lack of female debaters in the Southern African debating circuit.

 

 

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