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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

NBC tells Wayde’s story
2015-11-02

   

The film crew from NBC Olympics
filming Wayde van Niekerk (centre, in grey clothes)
during a practice session at Pellies Park on the
Bloemfontein Campus of the UFS.
On the left is Ans Botha, Van Niekerk’s coach.
Photo: Charl Devenish

The Kovsie star Wayde van Niekerk stands an excellent chance of shining at the 2016 Olympics and has a remarkable story behind his success.

This is why NBC Olympics, a division of the American broadcasting network NBC, selected the athlete from the University of the Free State (UFS) to do a special insert for the Olympics in Rio de Janeiro.

A film crew from NBC visited the City of Roses and the Bloemfontein Campus of the UFS on Monday 26 and Tuesday 27 October 2015 to film the insert. The feature will be screened on NBC Olympics’ platforms during and leading up to the Olympics next year.

One of four stars


Van Niekerk was one of four athletes used by the crew to film inserts on. The others were the South African swimmer Chad le Clos, the Kenyan 800 m athlete David Rudisha, and Ethiopian middle- and long-distance athlete Genzebe Dibaba.

The crew interviewed Van Niekerk and his coach Ans Botha, and also paid a visit to Pellies Park during one of his training sessions.

According to Tom Davidson, feature producer at NBC Olympics, the piece about Van Niekerk will be about three minutes long.

“We do a pretty good job of picking good stories, but it is up to the athletes to get there,” Davidson said.

“We think Wayde has a good shot at being in the finals of the 400 m at the Olympics.”

Van Niekerk won a gold medal in a time of 43.48 s at the World Championships in Beijing during August 2015 and set a new South African record for a third time and a new African record for a second time this year in the process.

Beijing success propels Wayde onto NBC radar


“Wayde’s performance in Beijing certainly propelled him onto our radar,” said Davidson.

 “He beat former World and Olympic champions like Kirani James and LaShawn Merritt.”

He feels that Van Niekerk is also very young and still at university.

And Botha makes his story even more interesting.

“It is not every day that you see a 74-year old great-grandmother coaching a world champion.”



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