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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Department of Education prescribes student’s novel to schools
2015-11-03


Ntshala Mahasa: The young storyteller

Three years ago Ntshala Mahase was an ordinary high school learner studying texts prescribed by the Department of Education. Now, other learners will be reading his brainchild, Life out of the Ordinary.

The third-year LLB student at the University of the Free State (UFS) officially launched his debut novel in July 2015 at the Bloemfontein Campus. Three months later, the work of fiction has reached a milestone of note. The novel has been selected as one of 12 books from young and emerging writers to form part of the Library and Information Association of South Africa’s (LIASA) Young Writers Programme.

LIASA is the regulatory body for South African public, school, and university libraries. Ntshala’s literary contribution is to be distributed to different school libraries, as per decision of the Western Cape and Gauteng Departments of Education.

About the book

The book narrates the transformational journey of a privileged suburban school boy who one day coincidently exposes himself to the harsh realities of an impoverished South African community. Tom then decides to make a difference and assist those who are less privileged. His experience out of his ordinary and secured Hyde Park life shakes him to such an extent that he falls into emotional anxiety and depression.

One in a thousand

Out of more than 200 entries, Life out of the Ordinary emerged as the only entry from outside the borders of the two provinces to make a set of 1 000 books recommended by LIASA to be prescribed by public schools as of 2016.

Ntshala was taken aback by the enthusiastic reception which his story attracted. “I am greatly humbled.This means it will rub shoulders with books by great South African authors like Niq Mhlongo, Zukiswa Wanner, Thando Mgqolozana, Zakes Mda and the likes,” he said. He is currently authoring his second novel.

 

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