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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Dean of Health Sciences receives prestigious international fellowship
2015-11-11



Dean of the Faculty of Health Science,
Prof Gert van Zyl

The Dean of our Faculty of Health Science, Prof Gert van Zyl, was admitted as an Inaugural Fellow of the Association for Medical Education in Europe (AMEE) at the annual conference in Glasgow.

This fellowship recognises members of AMEE who have demonstrated a consistent commitment to excellence in health professional education through scholarly contributions to the field over at least five years. Prof Van Zyl was honored with a Fellowship for his senior role related to education at the UFS, including his scholarly contributions. “This was an enormous privilege for me to be awarded the AMEE full Fellowship as one of only two South Africans to receive this honour from a prestigious organisation such as the AMEE. It also gives credit to the excellent work done by the team in the South African Association of Health Educationalists (SAAHE), and the Health Science Education team in the Faculty of Health Sciences at the UFS. All the leadership, hard work, and excellence over many years are acknowledged with this Fellowship. My appreciation to colleagues that motivated and inspired me during my academic journey to achieve this fellowship,” says Prof Van Zyl.

In seeking Fellowship of AMEE, applicants make a commitment to continue their leadership and the promotion of scholarship in health professional education into the future, as well as to the ongoing mentorship and development of more junior members who aspire to recognition at Associate Fellow or Fellow level. Fellows are expected to contribute actively to AMEE activities.

Prof Van Zyl was also recently appointed by the Minister of Health, Dr Aaron Motsoaledi, as Council Member representing Higher Education on the Health Professions Council of South Africa (HPCSA).

 

 

 

 

 

 

 

 

 

 

 

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