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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Clarinet lecturer honoured with prestigious international artistship
2015-11-13

Clarinetist Danré Strydom

Danré Strydom, lecturer in the Odeion School of Music (OSM) of the University at the Free State (UFS) has recently been added to the Buffet Crampon executive list of representative artist. Buffet Crampon is one of the most iconic woodwind brands and the leader in manufacturing first-rate clarinets. The artistship entails a highly competitive selection process to become the first South African Buffet Crampon brand ambassador.

Buffet-Crampon, based in France and Germany, is ailed internationally as the “Steinway” of clarinet manufacturers. The company follows a meticulous selection process, and the title of Buffet Artist is not bestowed lightly. Strydom will be the first South African artists to represent the brand.

For nearly 200 years, musicians have received continuous artistic excellence and a dedication to music from Buffet-Crampon and its instruments. In a dialogue with the most renowned artists, the brand’s ambition is to combine tradition with modernity, know-how with creation, and history with innovation in order to offer excellent wind instruments unique in character, and underpinned by undeniable quality.

Strydom received her formative musical education at the Windhoek Conservatoire, before completing her undergraduate degree at the UFS. Her playing then won her several prestigious scholarships for overseas studies. She began her postgraduate studies at Indiana University’s Jacobs School of Music, and then furthered her studies in Belgium, resulting in two separate Master’s Degrees in Clarinet and in Bass Clarinet Performance from the Royal Conservatory, Ghent University. 

Besides currently serving as principal clarinetist for the Free State Symphony Orchestra and Namibian National Symphony, she was an ad-hoc member of the esteemed Brussels Philharmonic from 2009-2013. The spell with the Brussels Philharmonic included an Academy Award for the soundtrack of the motion picture, “The Artist,” which Strydom considers one of her proudest moments.

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