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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Schoolgirl builds giant Gingerbread house for Children’s Wing Project
2015-11-13


Professor André Venter, Head: Department of Paediatrics and Child Health, Morgan Pelser, and Tertia de Bruin, Project Coordinator: Children’s Wing: UFS Marketing.
Photo: Leonie Bolleurs.

“You have to dream before your dreams can come true.” These words rang true for Morgan Pelser from Bloemfontein when she fulfilled her wish on Tuesday 3 November 2015 at the launch of her ‘big and real’ Gingerbread house.

 

Pelser, 13, said she had the idea of building the gingerbread house over six months ago and began working tirelessly, raising funds for the project. She intends to donate the money raised from this initiative to the Children’s Wing Project at Pelonomi and Universitas Hospitals. It was back in Grade 4 when she had the opportunity to tour through the ICU, neonatal and paediatric wards of the two hospitals, that she saw the need for better equipment and facilities. Pelser hopes to raise R200 000 through the initiative.

 

Professor André Venter, Head: Department of Paediatrics and Child Health at the University of the Free State, said he was greatly humbled by the perseverance and passion shown by Morgan in executing her dream. “I work with children, so I know how resilient they are, but seeing this is amazing. We tend to give up so easily,” he said. He went on to say that the money will be greatly appreciated, as it will be used to provide health-care facilities for children at both hospitals.

 

The launch of the gingerbread house was a huge success. The house is currently outside Coco C at the Loch Logan Waterfront. Members of the public are encouraged to see and taste the giant house, where they can leave a message on the inside of the house. A minimum fee of R20 is requested.

 

Professor André Venter, Head: Department of Paediatrics and Child Health, Morgan Pelser, and Tertia de Bruin, Project Coordinator: Children’s Wing: UFS-Marketing.

Photo: Leonie Bolleurs.

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