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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

First Dementia Care Mapper in Africa receives international award
2015-11-17

The first Dementia Care Mapper from Africa,
Dr Sanet du Toit.

Photo: iFlair Photography

“In one facility, four elders who needed minimal assistance to eat were provided with an opportunity to sit at a separate table, and enjoy their breakfast as preferred – that is, to spread bread with butter, jam or marmite; to add their own milk and sugar to their tea.”

Dr Sanet du Toit
described a scenario where staff members at an old-age home implemented recommendations she made following an observation she conducted.

“We do not think twice about doing this but, within institutional care settings, these ’normal’ routines are often replaced with practices that could be viewed as ‘time savers’. For example: everyone gets milky, sweet tea to drink,” she explains.

Yet, by creating an environment where the elderly living with dementia were at liberty to determine the amount of milk in their tea, active participation meant an improved well-being.

She was honoured with the International Association of Homes and Services for the Aging (IAHSA) Award for Excellence in Applied Research on 1 September 2015, at a joint conference held by the Aged & Community Services Australia (ACSA) and IAHSA in Perth.

This exceptional Occupational Therapist from the University of the Free State (UFS) emerged as the first Dementia Mapper from Africa. Dementia Care Mapping is a method used internationally to assess with the purpose of improving the quality of care given to residents in institutionalised settings.

The IAHSA award acknowledged her person-centered care training and research in South African residential care facilities while working at the UFS as a senior lecturer from 2003 to 2013. Currently, she is based at the University of Sydney, but remains an affiliated lecturer at the UFS Department of Occupational Therapy.

In 1992, she graduated with a BA in Occupational Therapy at the UFS, and went on to further her studies at various institutions. Also, she is one of the founding directors of the Eden Alternative South Africa, an advocacy for older persons’ rights within old-age homes. Over the years, Dr du Toit has won numerous awards for her research.

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