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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

5 things you might not know about Elizabeth Molapo: Miss SA 2016 finalist
2015-11-20

Kovsies’ own beauty queen, Elizabeth Molapo

Elizabeth Lihotetso Molapo is a final-year BCom Economics student at the University of the Free State. The impeccably-beautiful 23-year-old is the only Bloemfontein representative among the top 12 contestants who have their eyes fixed on the Miss South Africa 2016 crown.

You might not know that:


1. Elizabeth was named after Queen Elizabeth 2, with whom she shares a birthday. Her middle name, “Lihotetso”, translates as “Fire”. Suffice it to say, her burning desire to learn - the pull factor for her embarking on the Miss SA 2016 journey - is a manifestation of her fate.

2. This is not her first time in the Miss SA competition. Last year, Elizabeth gave the Miss SA competition a try but unfortunately did not make very far.

3. Her childhood dream was to become a pediatrician. Economics won when she had to shadow at a hospital when she was in high school, and was horrified at the sight of blood. Elizabeth then decided: “This isn’t for me!”

4. “Enter Miss SA,” she recalls Rolene Strauss saying. The former Miss SA and current Miss World encouraged her to follow her dreams, and to aim for the most prestigious tiara in the country.

5. The last book she read was Redeeming Love by Francine Rivers. It is also the next one she might read, as she has read it three times already.

Other Kovsies who have made strides in the beauty pageant realm include Rolene Strauss who was crowned Miss SA 2014 and Miss World 2015. Earlier this year, Relebohile Kobeli was also crowned Miss Lesotho 2015 and is now en route to Miss World International 2015 in China.

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