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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Master’s student awarded Mandela Rhodes scholarship
2015-11-25

 

Candice Thikeson’s name will be added to the Mandela Rhodes Scholars book
Photo: Valentino Ndaba

Candice Thikeson was recently selected as the only 2016 Mandela Rhodes Scholar from the University of the Free State. She is one of 50 young African postgraduate students, eager to contribute positively to the educational development of the continent.

The Mandela Rhodes scholarship is a fully-funded postgraduate scholarship awarded to promising future leaders by the Mandela Rhodes Foundation. It is named after the former president of our country, Nelson Mandela, and Cecil Rhodes, who was known for his business skills and political influence in South Africa. Instituted in 1999, the scholarship aims to advance scholars who demonstrate the principles of Leadership and Reconciliation embodied by Mandela and Rhodes’s legacy, as they relate specifically to Education and Entrepreneurship.

Thikeson expects the programme will educate her on how to integrate the four pillars in relation to her field of study.

For Thikeson, earning the scholarship served as an endorsement of her dream of becoming an academic. “I want to obtain a PhD, lecture at a university, publish papers, and speak at conferences,” she related. “I also want to produce academics, I want to mentor young people,” she added.

Her academic journey began in 2011 when she pursued a BA Fine Arts degree for a year. Thikeson then transferred to a BA General degree which she completed over two instead of the standard three years. She went on to study an Honours degree in Art History and Visual Culture Studies. In the same year, she travelled to Rijksuniversiteit Groningen (University of Groningen) in the Netherlands as part of an exchange agreement between the university and the UFS, where she completed her mini-dissertation in four months. Both her BA and Honours were passed with distinction. Currently, Thikeson is pursuing a Masters degree at the Department of Art History and Image Studies under the supervision of Prof Suzanne Human.

Some accolades to her name include the Jan Teurlinckx Prize for the best student in Art History (2011), the David Jacobs Prize, awarded to the best student in Philosophy (2013), and the Richard Miles Prize, presented by the Dean of the Faculty of the Humanities (2013). Thikeson was also selected as a member of the Golden Key Honour society in 2012, for her consistent academic excellence.

Last year, Lehlohonolo Mofokeng, Zola Valashiya, and Tumelo Morobane made the UFS proud by graduating as the class of 2015 Mandela Rhodes Scholars.

 

 

 

 

 

 

 

 

 

 

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