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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Student represents UFS and SA in world orchestra
2015-11-27



The A-list violist, Maja van Dyk 

Among the 100 musicians from 74 countries who performed at the Carnegie Hall in New York as part of the International Youth Philharmonic Orchestra (YPHIL) tour was Maja van Dyk. The viola player was one of two South Africans, and the only University of the Free State (UFS) representative, in the main performance of the tour on 27 September 2015.

“The highlight of the tour was definitely the concert in Carnegie Hall,” said Maja.

The fourth-year BMus student at the UFS Odeion School of Music (OSM) was one of 900 musicians between 18 and 26 years of age who auditioned for the world orchestra.  She reached a major milestone in her music career when she was selected as both our country and our university’s ambassador.

The YPHIL project is a hub for the most powerful young performers from all over the world who spotlight social issues affecting the global collective through music. This objective behind creating one symphonic voice is to unite and empower in an unconventional manner.

Over the years, Maja has gathered a wealth of experience by playing for the MIAGI Youth Orchestra, the South African National Youth Orchestra, the Free State Youth Orchestra, the OSM Camerata, and the Free State Symphony Orchestra, as well as the Bloemfontein and Stellenbosch City Orchestras.

As a member of the National Youth Orchestra, she was invited to tour the country with the world-class Zurich Chamber Orchestra and the Zürcher Kammerorchester in 2012 and 2013 respectively. Her recent international exposure cannot be separated from past stints on the world stage. “I participated in tours of The World Orchestra to Spain and Lebanon, prior to the YPhil tour to New York City this past September,” she said.

The award-winning Maja is currently playing as an ad hoc member for the Cape Town Philharmonic Orchestra. She moved to the Western Cape after she played in her last exam last week.

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