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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Palestinian delegation visit marks new bilateral relations
2015-11-27



Prof Jonathan Jansen and His Excellency Mr Hashem Dajani
Photo: Charl Devenish

The Office of International Affairs hosted the official visit of the Ambassador of Palestine, His Excellency Mr Hashem Dajani, to the University of the Free State (UFS) on 16-17 November 2015. Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, welcomed the Ambassador and the Palestinian delegation to the Bloemfontein Campus. During the visit, they met with senior management of the university, including Dr Karen Lazenby (Registrar: Systems and Administration), Beata Mtyingizana (Director of International Affairs) and JC Van der Merwe (Deputy Director at the Institute of Reconciliation and Social Justice).

The visit marked the finalisation of a scholarship initiative which offers placement of Palestinian students to study at the UFS. The new Vice-Chancellor’s International Scholarship programme will recognise academic excellence and merit in undergraduate, postgraduate, as well as doctoral academic disciplines.

One of the strategic objectives of the UFS is that of internationalisation, which is strengthened by the scholarship programme. With the focus on Palestine, the university’s international footprint in non-traditional regions of the world, such as the Middle East, will therefore be highlighted.

To conclude the visit, the Institute for Reconciliation and Social Justice hosted a film screening featuring ‘Jerusalem, the east side story’. The documentary mainly looks at the past forty years of Israeli military occupation policies in Jerusalem and the subsequent impact on the city and its people.

“Peace in Palestine is key to world peace,” Ambassador Dajani said. “The issue of self-determination is central to the Palestinian effort, and, through the assistance of the international community, it can it be realised.”

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