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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

3rd tri-annual Nursing Odyssey international conference
2007-05-29

 The School of Nursing at the University of the Free State (UFS) is hosting its 3rd tri-annual Nursing Odyssey international conference from 9-11 July 2007 on the Main Campus in Bloemfontein. Odyssey means an exciting journey. In a dynamic profession such as nursing, the Odyssey is never ending or boring.

This year the focus is on caring. Although the conference addresses a wide variety of topics, special areas such as midwifery and wound care have been accentuated. Speakers from the United States of America (USA) and the United Kingdom (UK) will be deriving papers and workshops like:

  • Foetal monitoring - technology from clinic to consultant. A live demonstration will be given where a pregnant woman situated in a clinic will be linked to a system that sends information directly to a consultant who can then advise the clinic staff on the best treatment.
  • NVIVO is a computer based program that assists qualitative researchers to analyze their data. This two day hands-on workshop will enable researchers to implement the NVIVO program.
  • The role of hand washing in infection control is well known. A practical participatory demonstration will illustrate to nurses how they unwittingly spread germs.

Although there is a lot of focus on midwifery and wound care there will something for everyone like workshops and papers on ethics, evidence based practice as well as student papers. With 17 workshops and more than 70 papers the delegates will spoiled for choice.

 Enquiries can be directed to Ms Desiré Smuts at 051 401 2965.
 

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