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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Success of Schools Partnership Programme embodies essence of UFS
2016-01-04

Description: Schools Partnership programme Tags: Schools Partnership programme

The everyday function and subsequent success of the SPP have come to embody the very essence of the UFS: inspiring excellence; transforming lives.

Addressing the urgent need for quality education at school level, the University of the Free State (UFS) established the Schools Partnership Project (SPP) in 2012. The aim of the project has been to turn ineffective schools into institutions producing outstanding results, thereby increasing the number and quality of first-year students at the UFS.

Within three years, the SPP has grown to include 68 primary and secondary schools across the Free State and the Sterkspruit area in the Eastern Cape. The programme is headed by Dr Peet Venter and run from the UFS South Campus. Expert mentors assist teachers and principals at these schools on a weekly basis, helping them to excel at their core functions. The programme’s success has been phenomenal.

Learner results from the SPP schools show a marked improvement compared to previous years. Teachers report that they have gained a broader understanding of the subjects they teach. “The university is doing a great job with this programme,” says one of the teachers. “We have developed a lot. We really appreciate this partnership.” Teachers not only gain substantial expertise in areas of planning, presentation, and subject knowledge; an increasing number of them have been receiving promotions, too.

The principals experience similar positive results, and regard the SPP as a productive contribution to their schools. The project has also established closer cooperation between principals and schools. This enables them to achieve common goals, share knowledge, and deal with challenges together.

An added spin-off of the programme has been the increased involvement of parents and care-givers. “We experience much more involvement from the community,” says mentor Danie Nieuwenhuizen. Parents start to take it upon themselves to tidy school grounds, care for vegetable gardens, and prepare food at school feeding schemes. Even the Sustained Silent Reading programme – that supplies magazines to learners – is now having an impact on households and communities. Many homes have never had magazines or other reading material before the reading programme.

The everyday function and subsequent success of the SPP have come to embody the very essence of the UFS: inspiring excellence; transforming lives.

 

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